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Search Results for " er-negative breast cancer "

4

Compounds

Cat No. Product Name Synonyms Targets
T8954 ML179 ML-179 Others
ML179 is a potent and selective inverse agonist of liver receptor homolog-1 (LRH1, NR5A2) with IC50 of 320 nM.
T1785 Palbociclib PD 0332991 CDK
Palbociclib (PD 0332991) is a CDK inhibitor that inhibits CDK4 and CDK6 (IC50=11/16 nM) and is orally active. Palbociclib has anti-tumorigenic activity and has investigational potential for use in ER-positive and HER2-ne...
T70686 HJC-0123
Downregulate phosphorylation of STAT3, increase the expression of cleaved caspase-3, inhibit cell cycle progression and promote apoptosis in breast and pancreatic cancer cells with low micromolar to nanomolar IC50 values...
T61923 ERRα antagonist-2
ERRα antagonist-2 (Compound 11) is a potential Reverse agonist of ERR α (estrogen receptor related receptor α) (IC50=0.80 μ M). ERRα antagonist-2 can inhibit the migration and invasion of ER-negative MDA-MB-231 cells. ER...
TargetMol